Jeffrey D Laskin Selected Research

Mustard Gas (Sulfur Mustard)

10/2022	Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix.
10/2021	Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-α antibody.
12/2020	Progressive Lung Injury, Inflammation, and Fibrosis in Rats Following Inhalation of Sulfur Mustard.
2/2020	Long-term Respiratory Effects of Mustard Vesicants.
1/2020	Expression of Laminin γ2 Proteolytic Fragments in Murine Skin Following Exposure to Sulfur Mustard.
1/2020	Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard.
9/2018	Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug.
4/2016	ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure.
1/2016	Multi-inhibitor prodrug constructs for simultaneous delivery of anti-inflammatory agents to mustard-induced skin injury.
1/2016	Mustard vesicants alter expression of the endocannabinoid system in mouse skin.

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Jeffrey D Laskin Research Topics

Disease

46	Inflammation (Inflammations) 10/2021 - 04/2002
34	Lung Injury 10/2021 - 04/2002
14	Edema (Dropsy) 10/2021 - 12/2010
12	Fibrosis (Cirrhosis) 01/2021 - 12/2012
12	Necrosis 09/2018 - 04/2002
11	Wounds and Injuries (Trauma) 05/2021 - 02/2012
9	Endotoxemia 02/2013 - 01/2002
7	Acute Lung Injury 10/2021 - 08/2014
7	Hyperplasia 01/2020 - 04/2002
7	Pneumonia (Pneumonitis) 01/2017 - 04/2002
6	Poisoning 02/2020 - 02/2011
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2020 - 03/2007
4	Neoplasms (Cancer) 10/2020 - 03/2008
4	Skin Diseases (Skin Disease) 01/2019 - 11/2002
4	Lung Diseases (Lung Disease) 12/2017 - 05/2002
3	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 11/2020 - 02/2011
3	Breast Neoplasms (Breast Cancer) 01/2019 - 08/2011
2	Corneal Injuries 10/2022 - 04/2016
2	Ataxia Telangiectasia (Louis Bar Syndrome) 06/2020 - 01/2019
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2019 - 12/2017
2	Asthma (Bronchial Asthma) 01/2019 - 12/2017
2	Vitiligo 08/2018 - 01/2018
2	Psoriasis (Pustulosis Palmaris et Plantaris) 08/2018 - 01/2018
2	Carcinogenesis 07/2014 - 10/2005
2	Bronchiolitis 06/2013 - 01/2011
1	Dyslipidemias (Dyslipidemia) 10/2020
1	Hyperoxia 01/2020

Drug/Important Bio-Agent (IBA)

21	Irritants (Vesicants)IBA 11/2020 - 06/2010
20	Mustard Gas (Sulfur Mustard)IBA 10/2022 - 06/2010
17	Mechlorethamine (Nitrogen Mustard)FDA Link 05/2021 - 01/2011
15	OzoneIBA 10/2020 - 04/2002
12	Proteins (Proteins, Gene)FDA Link 01/2019 - 04/2002
10	Alkylating AgentsIBA 01/2021 - 10/2011
10	Acetaminophen (Paracetamol)FDA LinkGeneric 07/2012 - 10/2002
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 10/2002
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2012 - 04/2002
6	Transaminases (Aminotransferases)IBA 07/2012 - 11/2003
5	EnzymesIBA 05/2021 - 03/2008
5	DNA (Deoxyribonucleic Acid)IBA 06/2020 - 10/2007
5	2-chloroethyl ethyl sulfideIBA 04/2016 - 12/2010
5	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 03/2015 - 04/2002
5	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2011 - 04/2002
4	Reactive Nitrogen SpeciesIBA 01/2019 - 08/2010
4	Cholinergic Agents (Cholinergics)IBA 12/2015 - 05/2010
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 10/2021 - 10/2011
3	CatalaseIBA 05/2021 - 06/2003
3	Messenger RNA (mRNA)IBA 01/2021 - 11/2002
3	Laminin (Merosin)IBA 01/2020 - 04/2013
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 03/2004
3	Connective Tissue Growth FactorIBA 01/2019 - 01/2011
3	Peptide Hydrolases (Proteases)FDA Link 01/2019 - 05/2002
3	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 11/2018 - 10/2013
3	ProdrugsIBA 09/2018 - 02/2012
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 03/2016 - 10/2010
3	NitrogenIBA 01/2016 - 05/2002
3	Galectin 3 (LGALS3)IBA 04/2015 - 09/2012
3	EicosanoidsIBA 06/2010 - 04/2002
3	Peroxynitrous Acid (Peroxynitrite)IBA 03/2008 - 08/2004
3	NF-kappa B (NF-kB)IBA 10/2007 - 03/2002
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2021 - 01/2019
2	CollagenIBA 12/2020 - 02/2005
2	LigandsIBA 10/2020 - 10/2002
2	DNA-Activated Protein KinaseIBA 06/2020 - 01/2019
2	Pharmaceutical PreparationsIBA 01/2019 - 02/2012
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2018 - 01/2016
2	Indomethacin (Indometacin)FDA LinkGeneric 09/2018 - 01/2016
2	Sulfides (Thioethers)IBA 09/2018 - 10/2014
2	AcetylcholinesteraseIBA 09/2018 - 01/2016
2	Photosensitizing Agents (Photosensitizers)IBA 08/2018 - 01/2018
2	QuinonesIBA 01/2017 - 08/2011
2	Oxygen (Dioxygen)IBA 01/2016 - 05/2002
2	Parathion (Ethyl Parathion)IBA 01/2016 - 10/2015
2	Cholinergic Antagonists (Anticholinergics)IBA 01/2016 - 02/2012
2	FibrinIBA 11/2015 - 12/2012
2	Protein CIBA 08/2014 - 09/2012
2	LipocalinsIBA 08/2014 - 10/2007
2	Surface-Active Agents (Surfactants)IBA 08/2014 - 09/2012
2	Toll-Like Receptor 4IBA 02/2013 - 12/2007
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2012 - 05/2010
2	LipopolysaccharidesIBA 10/2007 - 01/2002
1	Blood Proteins (Serum Proteins)IBA 10/2021
1	Fibrinogen (Factor I)FDA Link 10/2021
1	AntioxidantsIBA 05/2021
1	Histones (Histone)IBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	ChlorineIBA 11/2020
1	Chemical Warfare AgentsIBA 11/2020
1	PhosgeneIBA 11/2020
1	RicinIBA 11/2020
1	IminesIBA 10/2020
1	Growth InhibitorsIBA 10/2020
1	1,2,4-triazoleIBA 10/2020
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 06/2020
1	SmokeIBA 01/2020
1	Air Pollutants (Pollutants, Air)IBA 01/2020
1	AcidsIBA 01/2020
1	EndotoxinsIBA 01/2020
1	LipidsIBA 12/2019

Therapy/Procedure

7	Therapeutics 05/2021 - 01/2011
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 10/2020